BIBN-99
Based on 1 Customer Validation
BIBN-99 is a selective, BBB-penetrable and competitive muscarinic M2 receptor antagonist. BIBN-99 improves cognitive performancein rats with traumatic brain injury.
For research use only. We do not sell to patients.
- Purity: 98.02%
- CAS No.: 145301-48-0
- Formula: C31H42ClN5O3
- Molecular Weight:568.15
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 145301-48-0
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Appearance Solid
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Molecular Weight 568.15
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Formula C31H42ClN5O3
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Color White to off-white
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SMILES
CCCC(C)(C(N(CC)CCCC1CCN(CC1)CC(N2C3=NC=CC=C3NC(C4=CC(Cl)=CC=C42)=O)=O)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (88.00 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Doods H, et al. Characterization of BIBN 99: a lipophilic and selective muscarinic M2 receptor antagonist. Eur J Pharmacol. 1993 Sep 21;242(1):23-30. [Content Brief]
[2]. Pike BR, et al. Post-injury administration of BIBN 99, a selective muscarinic M2 receptor antagonist, improves cognitive performance following traumatic brain injury in rats. Brain Res. 1995 Jul 17;686(1):37-43. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7601 mL | 8.8005 mL | 17.6010 mL | 44.0025 mL |
| 5 mM | 0.3520 mL | 1.7601 mL | 3.5202 mL | 8.8005 mL | |
| 10 mM | 0.1760 mL | 0.8800 mL | 1.7601 mL | 4.4002 mL | |
| 15 mM | 0.1173 mL | 0.5867 mL | 1.1734 mL | 2.9335 mL | |
| 20 mM | 0.0880 mL | 0.4400 mL | 0.8800 mL | 2.2001 mL | |
| 25 mM | 0.0704 mL | 0.3520 mL | 0.7040 mL | 1.7601 mL | |
| 30 mM | 0.0587 mL | 0.2933 mL | 0.5867 mL | 1.4667 mL | |
| 40 mM | 0.0440 mL | 0.2200 mL | 0.4400 mL | 1.1001 mL | |
| 50 mM | 0.0352 mL | 0.1760 mL | 0.3520 mL | 0.8800 mL | |
| 60 mM | 0.0293 mL | 0.1467 mL | 0.2933 mL | 0.7334 mL | |
| 80 mM | 0.0220 mL | 0.1100 mL | 0.2200 mL | 0.5500 mL |
BIBN-99 Related Classifications
HY-119953 Related Classifications
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