VU0463841
VU0463841 is a potent, selective and brain-penetrant mGlu5 negative allosteric modulator (NAM) with an IC50 of 13 nM. VU0463841 is ineffective against mGlu1-4 and mGlu7-8. VU0463841 has the potential for the Cocaine addiction research.
For research use only. We do not sell to patients.
- CAS No.: 1439095-16-5
- Formula: C13H8ClFN4O
- Molecular Weight:290.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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mGlu5 Receptor 13 nM (IC50) |
Chemical Information
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CAS No. 1439095-16-5
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Molecular Weight 290.68
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Formula C13H8ClFN4O
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SMILES
O=C(NC1=NC=C(C=C1)Cl)NC2=CC(F)=CC(C#N)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)