2′-OMe-UMP
2′-OMe-UMP is a primer extension terminator. When 2′-OMe-UMP is present at the -1 position of the primer chain, its 2′-OMe group sterically clashes with the base of the next NTP at the active site (+1 position). This clash weakens the base-stacking interaction between the +1 position and the -1 position, thereby reducing the binding affinity of the next substrate.
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- No. CAS: 4214-23-7
- Fòrmula: C10H15N2O9P
- Peso molecular:338.21
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 4214-23-7
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Peso molecular 338.21
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Fòrmula C10H15N2O9P
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SMILES
O[C@H]1[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(O)(O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)