2′-OMe-UMP

2′-OMe-UMP is a primer extension terminator. When 2′-OMe-UMP is present at the -1 position of the primer chain, its 2′-OMe group sterically clashes with the base of the next NTP at the active site (+1 position). This clash weakens the base-stacking interaction between the +1 position and the -1 position, thereby reducing the binding affinity of the next substrate.

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  • No. CAS: 4214-23-7
  • Fòrmula: C10H15N2O9P
  • Peso molecular:338.21
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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