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Referencia número: HY-106090

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Teloxantrone

Name: Teloxantrone
Brand: MedChemExpress
SKU: HY-106090
Availability: PreOrder

(Synonyms: CI-937; DUP 937)

Teloxantrone (CI-937; DUP 937) is a DNA synthesis inhibitor (IC₅₀: 0.33 μM). Teloxantrone has antitumor activity and can be used in colorectal cancer research.

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No. CAS: 91441-48-4
Fòrmula: C₂₁H₂₅N₅O₄
Peso molecular:411.45

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Teloxantrone Chemical Structure

No. CAS: 91441-48-4

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Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

Teloxantrone (CI-937; DUP 937) is a DNA synthesis inhibitor (IC₅₀: 0.33 μM). Teloxantrone has antitumor activity and can be used in colorectal cancer research^[1]^[2].

Ver todos los productos específicos de isoformas DNA/RNA Synthesis :

Cellular Effect

Cell Line	Type	Value	Description	References
L1210	IC₅₀	1.4 x 10^-7M Compound: 74	Tested in vitro against murine L1210 leukemia. Tested in vitro against murine L1210 leukemia.	[PMID: 3806589]
L1210	IC₅₀	1.40E-07 M Compound: 74	Tested in vitro against murine L1210 leukemia. Tested in vitro against murine L1210 leukemia.	[PMID: 3806589]

Chemical Information

No. CAS 91441-48-4
Peso molecular 411.45
Fòrmula C₂₁H₂₅N₅O₄
SMILES

CNCCNC1=C2C3=C(C=C1)N(CCNCCO)N=C3C4=C(C(O)=CC=C4O)C2=O
Synonyms

CI-937; DUP 937
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Fry DW, et al. In vitro DNA strand scission and inhibition of nucleic acid synthesis in L1210 leukemia cells by a new class of DNA complexers, the anthra[1,9-cd]pyrazol-6(2H)-ones (anthrapyrazoles). Biochem Pharmacol. 1985 Oct 1;34(19):3499-508. [Content Brief]

[2]. Maroun JA, et al. Phase II study on DuP 937 (Teloxantrone) in colorectal carcinoma. A Canadian National Cancer Institute Clinical Trial Group study. Invest New Drugs. 1993 May-Aug;11(2-3):235-7. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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