1. Epigenetics
  2. Histone Methyltransferase
  3. EZH2-IN-5

EZH2-IN-5 

Cat. No.: HY-141566
Handling Instructions

EZH2-IN-5 is a potent EZH2 inhibitor with IC50 values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively.

For research use only. We do not sell to patients.

EZH2-IN-5 Chemical Structure

EZH2-IN-5 Chemical Structure

CAS No. : 1403258-69-4

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Description

EZH2-IN-5 is a potent EZH2 inhibitor with IC50 values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively[1].

IC50 & Target[1]

EZH2 WT

1.52 nM (IC50)

EZH2 Y641F mutant type

4.07 nM (IC50)

In Vitro

EZH2-IN-5 (compound 276) inhibits cell growth of WSUDLCL2 cell lines with an IC50 of 187.28 nM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

517.50

Formula

C₂₆H₃₇BrN₄O₂

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
EZH2-IN-5
Cat. No.:
HY-141566
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