EZH2-IN-5
EZH2-IN-5 is a potent EZH2 inhibitor with IC50 values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively.
For research use only. We do not sell to patients.
- CAS No.: 1403258-69-4
- Formula: C26H37BrN4O2
- Molecular Weight:517.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Histone Methyltransferase Isoforms
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Biological Activity
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EZH2 WT 1.52 nM (IC50) |
EZH2 Y641F mutant type 4.07 nM (IC50) |
EZH2-IN-5 (compound 276) inhibits cell growth of WSUDLCL2 cell lines with an IC50 of 187.28 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1403258-69-4
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Molecular Weight 517.50
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Formula C26H37BrN4O2
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SMILES
CCN([C@H]1CC[C@@H](CC1)N(C)C)C2=C(C(C(NCC3=C(C=C(NC3=O)C)C)=O)=CC(Br)=C2)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EZH2-IN-5 Related Classifications
HY-141566 Related Classifications
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