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  2. Fargesin

Fargesin 

Cat. No.: HY-N0719
Handling Instructions

Fargesin is a bioactive neolignan isolated from magnolia plants,with antihypertensive and anti-inflammatory effects.

For research use only. We do not sell to patients.

Fargesin Chemical Structure

Fargesin Chemical Structure

CAS No. : 31008-19-2

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Description

Fargesin is a bioactive neolignan isolated from magnolia plants,with antihypertensive and anti-inflammatory effects[1][2][3].

In Vitro

Fargesin exhibits anti-inflammation effects on THP-1 cells via suppression of PKC pathway including downstream JNK, nuclear factors AP-1 and NF-ĸB[3].
Fargesin as a potential β₁ adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis[4].

In Vivo

Fargesin has antihypertensive effect in 2K1C hypertensive rats via inhibiting oxidative stress and promoting NO release[1].

Molecular Weight

370.40

Formula

C₂₁H₂₂O₆

CAS No.

31008-19-2

SMILES

COC1=CC=C([[email protected]]2OC[[email protected]@]3([H])[[email protected]](C4=CC=C(OCO5)C5=C4)OC[[email protected]]32[H])C=C1OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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