Fasudil (Standard)
Fasudil (Standard) is the analytical standard of Fasudil (HY-10341A). This product is intended for research and analytical applications. Fasudil (HA-1077; AT877) is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein Kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil is also a potent Ca2+ channel antagonist and vasodilator.
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- CAS. Nr.: 103745-39-7
- Formel: C14H17N3O2S
- Molecular Weight:291.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 103745-39-7
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Molecular Weight 291.37
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Formel C14H17N3O2S
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SMILES
O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3)=O
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Synonyms
HA-1077 (Standard); AT877 (Standard)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Fasudil (Standard) Related Classifications
HY-10341AR Related Classifications
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Keywords
- Fasudil (Standard)
- 103745-39-7
- HA-1077 (Standard)
- AT877 (Standard)
- Reference Standards
- ROCK
- Calcium Channel
- Autophagy
- PKA
- PKC
- Rho-associated protein kinase
- Rho-associated kinase
- Rho-kinase
- ROK
- Ca2+ channels
- Ca channels
- Protein kinase A
- Protein kinase C
- orally active
- protein kinases
- collagen
- a-SMA
- TIMP-1
- ERK1/2
- JNK
- p38
- rat HSCs
- human HSC
- TWNT-4 cells
- Ca2+ channel antagonist
- vasodilator
- lysophoaphatidic acid
- LPA
- Inhibitor
- inhibitor
- inhibit