FGFR3-IN-3
FGFR3-IN-3 (compound 40a) is a potent and pan-FGFR inhibitor, with IC50s of 2.1 nM, 3.1 nM, 4.3 nM and 74 nM for FGFR1, 2, 3, and 4, respectively. FGFR3-IN-3 can be used for the research of bladder cancer.
For research use only. We do not sell to patients.
- CAS No.: 2428738-41-2
- Formula: C38H49N9O6S
- Molecular Weight:759.92
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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FGFR1 2.1 nM (IC50) |
FGFR2 3.1 nM (IC50) |
FGFR3 4.3 nM (IC50) |
FGFR4 74 nM (IC50) |
Chemical Information
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CAS No. 2428738-41-2
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Molecular Weight 759.92
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Formula C38H49N9O6S
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SMILES
CCNS(=O)(C1=C(C=CC=C1)NC2=NC(NC3=CC(OC)=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)=NC=C2NC(C6=CC(OC)=CC(OC)=C6)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)