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FM-479

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Based on 1 Customer Validation

FM-479 is the negative control of FM-381 (HY-102046) and has no activity on JAK3 or other kinases. FM-381 is a potent covalent reversible inhibitor of JAK3 targeting the unique Cys909. FM-381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively.

For research use only. We do not sell to patients.

  • Purity : 99.2%
  • CAS No.: 2226521-64-6
  • Formula: C25H26N6O2
  • Molecular Weight:442.51
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • FM-479 Chemical Structure
    FM-479 Chemical Structure
CAS No.: 2226521-64-6
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Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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All JAK Isoforms

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  • FM-479 Chemical Structure
    FM-479 Chemical Structure
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  • FM-479