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Taxifolin

(Synonyms: (+)-Dihydroquercetin; (+)-Taxifolin)
30 Cited Publications
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Based on 30 publication(s) in Google Scholar

Taxifolin ((+)-Dihydroquercetin) exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity.

For research use only. We do not sell to patients.

  • Purity: 99.92%
  • CAS No.: 480-18-2
  • Formula: C15H12O7
  • Molecular Weight:304.25
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Taxifolin Chemical Structure
    Taxifolin Chemical Structure
  • Experimental Validation Results for Taxifolin
  • Experimental Validation Results for Taxifolin
  • Experimental Validation Results for Taxifolin
  • Experimental Validation Results for Taxifolin
  • Experimental Validation Results for Taxifolin
  • Experimental Validation Results for Taxifolin
  • Experimental Validation Results for Taxifolin
CAS No.: 480-18-2
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  • Taxifolin Chemical Structure
    Taxifolin Chemical Structure
    1/16
  • 1/16

    Taxifolin purchased from MedChemExpress. Usage Cited in: Front Immunol. 2025 Mar 17:16:1532336. [Abstract]

    Customer Validation
     After infection of MDCK cells with H1N1-UI182 at an MOI of 0.01, the cells were treated with Quercetin (10 µM), Taxifolin (50 µM), Miquelianin (100 µM), and Baloxavir (10 µM) for 48 h. Nuclei were stained with DAPI, and infected cells were detected by NP-specific immunofluorescence staining (scale bar: 100 µm).

  • 1/16

    Taxifolin purchased from MedChemExpress. Usage Cited in: Vet Sci. 2024 Mar 30;11(4):156. [Abstract]

    Customer Validation
     IPEC-J2 cells were treated with Taxifolin (0, 50, 100, 150, 300, and 400 μM) for 24 h. Cell viability was determined using the CCK-8 assay.

  • 1/16

    Taxifolin purchased from MedChemExpress. Usage Cited in: Vet Sci. 2024 Mar 30;11(4):156. [Abstract]

    Customer Validation
     After pretreating the cells with 150 μM Taxifolin (0-150 μM) for 24 h, they were exposed to 0.5 μg/mL DON for another 24 h. Then, cell morphology was evaluated by capturing images of the cells. The cyan arrows indicate shrunken or fragmentated cells; the yellow arrows indicate normal or dividing cells. The magnification is 40×.

  • 1/16

    Taxifolin purchased from MedChemExpress. Usage Cited in: Vet Sci. 2024 Mar 30;11(4):156. [Abstract]

    Customer Validation
     Representative immunofluorescence images of the control, Taxifolin, DON, and Taxifolin (0-150 μM) + DON groups labeled with DAPI (blue) and anti-Ki67 antibody (red).

  • 1/16

    Taxifolin purchased from MedChemExpress. Usage Cited in: Vet Sci. 2024 Mar 30;11(4):156. [Abstract]

    Customer Validation
     Effect of Taxifolin on intracellular ROS levels. Fluorescence values were determined using a fluorescence microplate. Data are shown as mean ± SEM (n = 3). Control: control group; 150 μM TA: 150 μM Taxifolin group; DON: 0.5 μg/mL DON group; 150 μM Taxifolin + DON: 150 μM Taxifolin + 0.5 μg/mL DON group.

  • 1/16

    Taxifolin purchased from MedChemExpress. Usage Cited in: Molecules. 2021 Mar 5;26(5):1409. [Abstract]

    Customer Validation
     Time course of SARS-CoV-2 Mpro enzymatic activity in response to inhibitory compounds. Black, green, red, and yellow dots represent control, 100 µM Taxifolin, 95.6 µM Silybin A + Silybin B, and 100 µM GC376, respectively. Reported traces are the average of three experiments.

  • 1/16

    Taxifolin purchased from MedChemExpress. Usage Cited in: Appl Microbiol Biotechnol. 2018 Feb;102(3):1443-1453. [Abstract]

    Customer Validation
     Dihydroquercetin relieves APAP-induced necrosis and suppressed ERK/JNK stress responses. Western Blot analysis for phosphor-JNK1/2, β-Actin as a lading control.

  • Taxifolin