C5 Lenalidomide
Based on 1 Customer Validation
C5 Lenalidomide is a 5-amino-substituted Thalidomide (HY-14658) analog. C5 Lenalidomide inhibits LPS (HY-D1056)-stimulated TNF-α production.
For research use only. We do not sell to patients.
- Purity: 99.40%
- CAS No.: 191732-70-4
- Formula: C13H13N3O3
- Molecular Weight:259.26
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Apoptosis Compound Library
HY-L003
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Immunology/Inflammation Compound Library
HY-L007
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Differentiation Inducing Compound Library
HY-L038
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Angiogenesis-Related Compound Library
HY-L088
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Antidepressant Compound Library
HY-L108
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Anti-Prostate Cancer Compound Library
HY-L124
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Anti-Pulmonary Fibrosis Compound Library
HY-L125
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Cancer Stem Cells Compound Library
HY-L135
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Pain-Related Compound Library
HY-L139
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Mitochondrial Protection Compound Library
HY-L144
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Membrane Protein-targeted Compound Library
HY-L149
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Membrane Receptor-targeted Compound Library
HY-L150
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Autoimmune Disease Compound Library
HY-L156
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Cytokine Inhibitors Library
HY-L161
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Radioprotector Library
HY-L178
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
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Anti-Rheumatic Arthritis Compound Library
HY-L210
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3D Diverse Fragment Library
HY-L903
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MCE Kinase Hinge Binder Fragment Library
HY-L907
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Molecular Glue-like Compound Library
HY-L918
Biological Activity
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Cereblon |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | IC50 |
>100 μM
Compound: Page no 420, R4C1, cpd 1
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Antiinflammatory activity in human PBMC cells assessed as reduction in LPS-induced TNF-alpha production preincubated for 1 hr followed by LPS addition and measured after 18 to 20 hrs by ELISA
Antiinflammatory activity in human PBMC cells assessed as reduction in LPS-induced TNF-alpha production preincubated for 1 hr followed by LPS addition and measured after 18 to 20 hrs by ELISA
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[PMID: 31125896] |
Chemical Information
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CAS No. 191732-70-4
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Appearance Solid
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Molecular Weight 259.26
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Formula C13H13N3O3
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Color Gray to dark gray
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SMILES
O=C(C(N(CC1=C2C=CC(N)=C1)C2=O)CC3)NC3=O
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Synonyms
Lenalidomide 5'-amine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL (192.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8571 mL | 19.2857 mL | 38.5713 mL | 96.4283 mL |
| 5 mM | 0.7714 mL | 3.8571 mL | 7.7143 mL | 19.2857 mL | |
| 10 mM | 0.3857 mL | 1.9286 mL | 3.8571 mL | 9.6428 mL | |
| 15 mM | 0.2571 mL | 1.2857 mL | 2.5714 mL | 6.4286 mL | |
| 20 mM | 0.1929 mL | 0.9643 mL | 1.9286 mL | 4.8214 mL | |
| 25 mM | 0.1543 mL | 0.7714 mL | 1.5429 mL | 3.8571 mL | |
| 30 mM | 0.1286 mL | 0.6429 mL | 1.2857 mL | 3.2143 mL | |
| 40 mM | 0.0964 mL | 0.4821 mL | 0.9643 mL | 2.4107 mL | |
| 50 mM | 0.0771 mL | 0.3857 mL | 0.7714 mL | 1.9286 mL | |
| 60 mM | 0.0643 mL | 0.3214 mL | 0.6429 mL | 1.6071 mL | |
| 80 mM | 0.0482 mL | 0.2411 mL | 0.4821 mL | 1.2054 mL | |
| 100 mM | 0.0386 mL | 0.1929 mL | 0.3857 mL | 0.9643 mL |
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