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Referencia número: HY-P0300

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Bak BH3

Bak BH3 is derived from the BH3 domain of Bak, can antagonize the function of Bcl-xL in cells.

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No. CAS: 300349-67-1
Fòrmula: C₇₂H₁₂₅N₂₅O₂₄
Peso molecular:1724.90

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Bak BH3 Chemical Structure

No. CAS: 300349-67-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

Bak BH3 is derived from the BH3 domain of Bak, can antagonize the function of Bcl-xL in cells.

IC₅₀ & Target

^[1]

Bcl-xL

Ver todos los productos específicos de isoformas Bcl-2 Family :

In Vitro

Bak BH3 peptide antagonize the protective effects of microinjected Bcl-xL in α-Fas-treated HeLa cells, whereas a mutant Bak BH3 peptide that no longer binds Bcl-xL is inactive^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

No. CAS 300349-67-1
Peso molecular 1724.90
Fòrmula C₇₂H₁₂₅N₂₅O₂₄
Sequence

Gly-Gln-Val-Gly-Arg-Gln-Leu-Ala-Ile-Ile-Gly-Asp-Asp-Ile-Asn-Arg
Sequence Shortening

GQVGRQLAIIGDDINR
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Holinger EP, et al. Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases. J Biol Chem. 1999 May 7;274(19):13298-304. [Content Brief]

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Volume _(final) Volume _(final)

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Bak BH3

Ver todos los productos específicos de isoformas Bcl-2 Family

Actividad biológica

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In Vitro

Chemical Information

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Referencias

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