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Referencia número: HY-U00176

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Org30958

Org30958 is a potent aromatase inhibitor in vivo.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 99957-90-1
Fòrmula: C₂₁H₃₀O₂S₂
Peso molecular:378.59

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Org30958 Chemical Structure

No. CAS: 99957-90-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

Org30958 is a potent aromatase inhibitor in vivo.

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Aromatase

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In Vivo

Besides inhibition of cornification of vaginal epithelium Org30958 (ORG 30958) decreases ovarian aromatase and plasma E2 levels in DHEAS-treated hypophysectomized rats. Plasma estradiol levels are also lowered by Org30958 in dogs which are treated with pregnant mare serum gonadotrophin in order to induce pro-estrus. Org30958 displays much less than 1/400th of the androgenic activity of testosterone propionate in immature castrated rats and appears to be devoid of estrogenic and anti-estrogenic activity in ovariectomized mature rats. A twice daily dose of 1.5 mg Org30958/kg postpones ovulation in mature female rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 99957-90-1
Peso molecular 378.59
Fòrmula C₂₁H₃₀O₂S₂
SMILES

CCSSC[C@@]12[C@]3([H])[C@](CCC1=CC(CC2)=O)([H])[C@@]4([H])[C@@](C)(C(CC4)=O)CC3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Geelen JA, et al. Selection of 19-(ethyldithio)-androst-4-ene-3,17-dione (ORG 30958): a potent aromatase inhibitor in vivo. J Steroid Biochem Mol Biol. 1991 Feb;38(2):181-8. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Org30958

Ver todos los productos específicos de isoformas Cytochrome P450

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