(±) Anabasine
Based on 2 publication(s) in Google Scholar
(±) Anabasine is the racemate of Anabasine (HY-B1532). Anabasine is an agonist of α7nAChR and exhibits anti-inflammatory and insecticidal activities.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 98.55%
- No. CAS: 13078-04-1
- Fòrmula: C10H14N2
- Peso molecular:162.24
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Almacenamiento:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Traditional Chinese Medicine Active Compound Library
HY-L065
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HY-L071
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Food-Sourced Compound Library
HY-L094
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RO5 Drug-like Natural Product Library
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Mass Spectrometry Human Metabolite Library
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Natural Product Library
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Publications Citing Use of MedChemExpress (MCE) (±) Anabasine
MoreVer todos los productos específicos de isoformas Endogenous Metabolite
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Actividad biológica
Chemical Information
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No. CAS 13078-04-1
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Appearance Liquid (Density: 1.05 g/cm3 )
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Peso molecular 162.24
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Fòrmula C10H14N2
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Color Light yellow to orange
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SMILES
C1(C2NCCCC2)=CC=CN=C1
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
Solvente y solubilidad
DMSO : 130 mg/mL (801.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.17 mg/mL (13.38 mM); Clear solution
This protocol yields a clear solution of ≥ 2.17 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (21.7 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.17 mg/mL (13.38 mM); Clear solution
This protocol yields a clear solution of ≥ 2.17 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (21.7 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureza y Documentación
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Ficha de datos (273 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.1637 mL | 30.8185 mL | 61.6371 mL | 154.0927 mL |
| 5 mM | 1.2327 mL | 6.1637 mL | 12.3274 mL | 30.8185 mL | |
| 10 mM | 0.6164 mL | 3.0819 mL | 6.1637 mL | 15.4093 mL | |
| 15 mM | 0.4109 mL | 2.0546 mL | 4.1091 mL | 10.2728 mL | |
| 20 mM | 0.3082 mL | 1.5409 mL | 3.0819 mL | 7.7046 mL | |
| 25 mM | 0.2465 mL | 1.2327 mL | 2.4655 mL | 6.1637 mL | |
| 30 mM | 0.2055 mL | 1.0273 mL | 2.0546 mL | 5.1364 mL | |
| 40 mM | 0.1541 mL | 0.7705 mL | 1.5409 mL | 3.8523 mL | |
| 50 mM | 0.1233 mL | 0.6164 mL | 1.2327 mL | 3.0819 mL | |
| 60 mM | 0.1027 mL | 0.5136 mL | 1.0273 mL | 2.5682 mL | |
| 80 mM | 0.0770 mL | 0.3852 mL | 0.7705 mL | 1.9262 mL | |
| 100 mM | 0.0616 mL | 0.3082 mL | 0.6164 mL | 1.5409 mL |
(±) Anabasine Related Classifications
HY-W052144 Related Classifications
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