Abiprubart
Based on 1 Customer Validation
Abiprubart is an anti-CD40 human IgG4 κ monoclonal antibody. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.00%
- No. CAS: 2765071-95-0
- Peso molecular:144.036 kDa
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas TNF Receptor
More
Actividad biológica
Descripciòn
Isotype
Human IgG4 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
CD40
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Gene ID
Accession
P25942-1
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
-
Human IgG4 kappa
Aplicación
ELISA, FACS, Functional assay
Verified Bioactivity
-
Loaded CD40 Protein, Human (HEK293, His, HY-P73499A) on AHC2 biosensor, can bind Abiprubart with an affinity constant of 2.792E-09 M as determined in BLI assay. -
Flow Cytometry analysis of Raji cells labelling CD40 (red) with Abiprubart (anti-CD40) (HY-P990726). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG4 kappa (HY-P99003). Black-Unlabelled control, cells without incubation with primary antibody.
Chemical Information
-
No. CAS 2765071-95-0
-
Appearance Liquid
-
Peso molecular 144.036 kDa
-
Color Colorless to light yellow
-
Synonyms
KPL-404
-
Envío
Shipping with dry ice.
-
Formulation
Please refer to the lot-specific COA for specific buffer information.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
-
Ficha de datos (253 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Inhibitory Antibodies User Guide (603 KB)
Referencias
[1]. Abiprubart
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)