Anticancer agent 344
Anticancer agent 344 is a heterobifunctional anticancer compound with moderate cancer cell growth inhibitory activity, and it also exhibits inhibitory activity against ERα-overexpressing cells. Anticancer agent 344 can be used in cancer-related research.
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- No. CAS: 3099598-95-2
- Fòrmula: C51H55N7O3S
- Peso molecular:846.09
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
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ERα |
Anticancer agent 344 (III-189) exhibits moderate antiproliferative activity against MCF7 cells (GI50 = 0.05-0.5 μM)[1].
The anticancer agent 344 exhibits potent inhibitory activity against Doxorubicin (HY-15142A)-induced ERα-overexpressing T-Rex 293 cells (GI50 < 0.05 μM), and moderate inhibitory activity against normal T-Rex 293 cells (GI50 = 0.05-0.5 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 3099598-95-2
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Peso molecular 846.09
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Fòrmula C51H55N7O3S
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SMILES
CC1=C(C)SC2=C1C(C3=CC=C(N4CCC(O)(CC4)CN5CCN(C6=CC=C([C@H]7C8=CC=C(C(O)=O)C=C8CC[C@H]7C9=CC=CC=C9)C=C6)CC5)C=C3)=N[C@@H](C)C%10=NN=C(C)N2%10
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 344 Related Classifications
HY-184947 Related Classifications
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