Anticancer agent 353
Anticancer agent 353 is a heterobifunctional antitumor agent with weak ERα inhibitory activity and anticancer activity. Anticancer agent 353 exhibits growth inhibitory activity against MCF7 cells. Anticancer agent 353 can be used in cancer research.
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- No. CAS: 3099598-10-1
- Fòrmula: C52H58N8OS
- Peso molecular:843.13
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
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ERα |
Anticancer agent 353 (III-146) exhibits growth inhibitory activity against MCF7 cells, with a GI50 of < 0.05 μM[1].
Anticancer agent 353 exhibits activity in both Doxorubicin (HY-15142A)-induced ERα-overexpressing and non-induced T-Rex 293 cells, with consistent antiproliferative activity between the two groups (GI50 = 0.5-2.5 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 3099598-10-1
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Peso molecular 843.13
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Fòrmula C52H58N8OS
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SMILES
OC1=CC=C([C@@H](C2=CC=C(N3CC(C3)CN4CCN(CC4)CC5CN(C6=CC=C(C7=N[C@H](C)C8=NN=C(C)N8C9=C7C(C)=C(C)S9)C=C6)C5)C=C2)[C@@H](C%10=CC=CC=C%10)CC%11)C%11=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 353 Related Classifications
HY-184961 Related Classifications
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