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Referencia número: HY-115721

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Antimalarial agent 2

Antimalarial agent 2 is a novel orally efficacious antimalarials that suggests a fast in vitro killing profile.

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No. CAS: 2829950-49-2
Fòrmula: C₂₇H₂₅N₃O₅
Peso molecular:471.50

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Antimalarial agent 2 Chemical Structure

No. CAS: 2829950-49-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
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- IC₅₀ & Target
- Cellular Effect
Chemical Information
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Actividad biológica

Descripciòn

Antimalarial agent 2 is a novel orally efficacious antimalarials that suggests a fast in vitro killing profile.

IC₅₀ & Target

Plasmodium

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Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	CC₅₀	>40 μM Compound: 19f	Cytotoxicity against human HEK293 cells assessed as cell viability incubated for 72 hrs by Alamar blue assay Cytotoxicity against human HEK293 cells assessed as cell viability incubated for 72 hrs by Alamar blue assay	[PMID: 34437804]

Chemical Information

No. CAS 2829950-49-2
Peso molecular 471.50
Fòrmula C₂₇H₂₅N₃O₅
SMILES

O=C(O)C1=CC=C(COCC2=CC=CC(N=C(C(NCC3=CC=CC(CC)=C3)=O)N4)=C2C4=O)C=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Laleu B, et al. Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials. J Med Chem. 2021 Sep 9;64(17):12582-12602. [Content Brief]

Calculators

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Calculadora de dilución

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Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Antimalarial agent 2

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