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Referencia número: HY-N16402

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Aspergillusidone D

Aspergillusidone D (Compound 1), a brominated depsidone, is a Aromatase inhibitor with an IC₅₀ of 0.8  μM. Aspergillusidone D can be isolated from fungus Aspergillus unguis cultured in KBr medium. Aspergillusidone D has potent cytotoxicity against cancers cells, such as MOLT-3 cells. Aspergillusidone D can be used for cancers like breast cancer research.

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No. CAS: 1454585-77-3
Fòrmula: C₁₉H₁₆Br₂O₅
Peso molecular:484.14

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Aspergillusidone D Chemical Structure

No. CAS: 1454585-77-3

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Bioz

Actividad biológica

Descripciòn

IC₅₀ & Target^[1]

Aromatase

0.8 μM (IC₅₀)

Ver todos los productos específicos de isoformas Cytochrome P450 :

Ver todos los productos específicos de isoformas Endogenous Metabolite :

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	23.72 μM Compound: 1	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 15 mins prior to LPS challenge measured after 20 hrs by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 15 mins prior to LPS challenge measured after 20 hrs by Griess assay	[PMID: 24016057]

Chemical Information

No. CAS 1454585-77-3
Peso molecular 484.14
Fòrmula C₁₉H₁₆Br₂O₅
SMILES

C/C=C(C1=C2C(OC(C3=C(C)C(Br)=C(O)C=C3O2)=O)=C(C(O)=C1Br)C)\C
Structure Classification
- Others
Initial Source
- Microorganisms
Aspergillus unguis
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Sureram S, et al. Directed biosynthesis through biohalogenation of secondary metabolites of the marine-derived fungus Aspergillus unguis[J]. RSC advances, 2013, 3(6): 1781-1788.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Aspergillusidone D

Ver todos los productos específicos de isoformas Cytochrome P450

Ver todos los productos específicos de isoformas Endogenous Metabolite

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Aspergillusidone D Related Classifications

HY-N16402 Related Classifications