Bosakitug
Based on 1 Customer Validation
Bosakitug (BSI-045B) is an TSLP-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001). Bosakitug can be used in the research of inflammatory diseases such as moderate to severe atopic dermatitis.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.00%
- No. CAS: 2762183-23-1
- Peso molecular:145.507 kDa
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
TSLP
In Vitro
TSLP is a key regulator of type 2 (Th2) immune responses at the barrier surfaces of the skin, respiratory tract, and gastrointestinal tract. The expression level of TSLP is significantly elevated in models of atopic diseases such as atopic dermatitis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Gene ID
Accession
Q969D9-1
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-kappa
Aplicación
ELISA, FACS, Functional assay
Verified Bioactivity
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Loaded Bosakitug on AHC2 biosensor, can bind TSLP Protein, Human (HEK293, His, HY-P70818) with an affinity constant of 4.639E-10 M as determined in BLI assay.
Chemical Information
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No. CAS 2762183-23-1
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Appearance Liquid
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Peso molecular 145.507 kDa
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Color Colorless to light yellow
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SMILES
[Bosakitug]
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Synonyms
BSI-045B; TQC2731
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Envío
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Ficha de datos (256 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Inhibitory Antibodies User Guide (603 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bosakitug Related Classifications
HY-P990906 Related Classifications
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