Burimamide
Burimamide is a blocker of histamine H2-receptor. Burimamide inhibits gastric acid secretion evoked by Pentagastrin (HY-A0261) or Gastrin. Burimamide also has alpha-adrenoceptor blocking activity. Burimamide in combination with the H1-receptor antagonist Mepyramine (HY-B1281) shows anti-inflammatory activity in a rat paw edema model induced by Compound 48/80 (HY-115768).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 34970-69-9
- Fòrmula: C9H16N4S
- Peso molecular:212.32
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas Histamine Receptor
MoreVer todos los productos específicos de isoformas Adrenergic Receptor
More
Actividad biológica
Chemical Information
-
No. CAS 34970-69-9
-
Peso molecular 212.32
-
Fòrmula C9H16N4S
-
SMILES
S=C(NCCCCC1=CN=CN1)NC
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Brimblecombe RW, et al. The pharmacology of burimamide and metiamide, two histamine H2-receptor antagonists. Fed Proc. 1976 Jun;35(8):1931-4. [Content Brief]
[2]. Gupta SC, et al. Azadirone, a limonoid tetranortriterpene, induces death receptors and sensitizes human cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through a p53 protein-independent mechanism: evidence for the role of the ROS-ERK-CHOP-death receptor pathway. J Biol Chem. 2013 Nov 8;288(45):32343-32356. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)