C5 Lenalidomide
Based on 1 Customer Validation
C5 Lenalidomide is a 5-amino-substituted Thalidomide (HY-14658) analog. C5 Lenalidomide inhibits LPS (HY-D1056)-stimulated TNF-α production.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.40%
- No. CAS: 191732-70-4
- Fòrmula: C13H13N3O3
- Peso molecular:259.26
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Almacenamiento:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Ver todos los productos específicos de isoformas TNF Receptor
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Actividad biológica
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Cereblon |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | IC50 |
>100 μM
Compound: Page no 420, R4C1, cpd 1
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Antiinflammatory activity in human PBMC cells assessed as reduction in LPS-induced TNF-alpha production preincubated for 1 hr followed by LPS addition and measured after 18 to 20 hrs by ELISA
Antiinflammatory activity in human PBMC cells assessed as reduction in LPS-induced TNF-alpha production preincubated for 1 hr followed by LPS addition and measured after 18 to 20 hrs by ELISA
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[PMID: 31125896] |
Chemical Information
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No. CAS 191732-70-4
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Appearance Solid
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Peso molecular 259.26
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Fòrmula C13H13N3O3
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Color Gray to dark gray
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SMILES
O=C(C(N(CC1=C2C=CC(N)=C1)C2=O)CC3)NC3=O
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Synonyms
Lenalidomide 5'-amine
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvente y solubilidad
DMSO : 50 mg/mL (192.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Portuguese - PT (419 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8571 mL | 19.2857 mL | 38.5713 mL | 96.4283 mL |
| 5 mM | 0.7714 mL | 3.8571 mL | 7.7143 mL | 19.2857 mL | |
| 10 mM | 0.3857 mL | 1.9286 mL | 3.8571 mL | 9.6428 mL | |
| 15 mM | 0.2571 mL | 1.2857 mL | 2.5714 mL | 6.4286 mL | |
| 20 mM | 0.1929 mL | 0.9643 mL | 1.9286 mL | 4.8214 mL | |
| 25 mM | 0.1543 mL | 0.7714 mL | 1.5429 mL | 3.8571 mL | |
| 30 mM | 0.1286 mL | 0.6429 mL | 1.2857 mL | 3.2143 mL | |
| 40 mM | 0.0964 mL | 0.4821 mL | 0.9643 mL | 2.4107 mL | |
| 50 mM | 0.0771 mL | 0.3857 mL | 0.7714 mL | 1.9286 mL | |
| 60 mM | 0.0643 mL | 0.3214 mL | 0.6429 mL | 1.6071 mL | |
| 80 mM | 0.0482 mL | 0.2411 mL | 0.4821 mL | 1.2054 mL | |
| 100 mM | 0.0386 mL | 0.1929 mL | 0.3857 mL | 0.9643 mL |
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