CB-182804
CB-182804, Polymyxin B (HY-149179) analogue, is a polypeptide antibiotic. CB-182804 has inhibitory activity against all Gram-negative pathogenic bacteria, including Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa with MIC50 values of 2 μg/mL. CB-182804 is mainly used for the research on refractory infections caused by multidrug-resistant (MDR) Gram-negative bacteria.
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- No. CAS: 1231767-35-3
- Fòrmula: C54H86ClN17O13
- Peso molecular:1216.82
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
>300 μM
Compound: 13
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Cytotoxicity against human HepG2 cells after 24 hrs by resazurin assay
Cytotoxicity against human HepG2 cells after 24 hrs by resazurin assay
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[PMID: 26734854] |
Chemical Information
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No. CAS 1231767-35-3
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Peso molecular 1216.82
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Fòrmula C54H86ClN17O13
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SMILES
O=C(N[C@H](C(N[C@@](C(N[C@H](C(N[C@]([C@H](O)C)([H])C(NCC[C@@](NC([C@H](CCN)NC([C@@]([C@H](O)C)([H])NC([C@H](CCN)NC(NC1=C(C=CC=C1)Cl)=O)=O)=O)=O)([H])C(N[C@@H](CCN)C2=O)=O)=O)=O)CCN)=O)([H])CCN)=O)CC(C)C)[C@H](N2)CC3=CC=CC=C3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CB-182804 Related Classifications
HY-107120 Related Classifications
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