Cyfluthrin
Based on 1 Customer Validation
Cyfluthrin is a type II pyrethroid and has effects on various insects. Cyfluthrin is a modulator of Nav1.8 sodium channels by repetitive stimulation. Cyfluthrin can be applied in agriculture,veterinary, insecticide,pyrethroid and stored product.
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- Pureza: 99.52%
- No. CAS: 68359-37-5
- Fòrmula: C22H18Cl2FNO3
- Peso molecular:434.29
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Almacenamiento:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
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Nav1.8 |
Cyfluthrin (0-50 μM; 24 hours) is against SH-SY5Y cell growth with an IC50 and an IC30 of 19.39 μM and 4.81 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 68359-37-5
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Appearance Oil
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Peso molecular 434.29
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Fòrmula C22H18Cl2FNO3
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Color Light yellow to yellow
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SMILES
O=C(C1C(C)(C)C1/C=C(Cl)\Cl)OC(C#N)C2=CC=C(F)C(OC3=CC=CC=C3)=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : ≥ 200 mg/mL (460.52 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (276 KB)
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SDS (729 KB)
- English - EN (729 KB)
- Français - FR (729 KB)
- Deutsch - DE (729 KB)
- Norwegian - NO (729 KB)
- Español - ES (729 KB)
- Swedish - SV (729 KB)
- Italian - IT (729 KB)
- Korean - KR (729 KB)
- Portuguese - PT (729 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Jin-Sung Choi,et al.Structure-activity Relationships for the Action of 11 Pyrethroid Insecticides on Rat Na v 1.8 Sodium Channels Expressed in Xenopus Oocytes.Toxicol Appl Pharmacol. 2006 Mar 15;211(3):233-44 [Content Brief]
[2]. María-Aránzazu Martínez, et al. Oxidative Stress and Related Gene Expression Effects of Cyfluthrin in Human Neuroblastoma SH-SY5Y Cells: Protective Effect of Melatonin. Environ Res. 2019 Oct;177:108579. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3026 mL | 11.5130 mL | 23.0261 mL | 57.5652 mL |
| 5 mM | 0.4605 mL | 2.3026 mL | 4.6052 mL | 11.5130 mL | |
| 10 mM | 0.2303 mL | 1.1513 mL | 2.3026 mL | 5.7565 mL | |
| 15 mM | 0.1535 mL | 0.7675 mL | 1.5351 mL | 3.8377 mL | |
| 20 mM | 0.1151 mL | 0.5757 mL | 1.1513 mL | 2.8783 mL | |
| 25 mM | 0.0921 mL | 0.4605 mL | 0.9210 mL | 2.3026 mL | |
| 30 mM | 0.0768 mL | 0.3838 mL | 0.7675 mL | 1.9188 mL | |
| 40 mM | 0.0576 mL | 0.2878 mL | 0.5757 mL | 1.4391 mL | |
| 50 mM | 0.0461 mL | 0.2303 mL | 0.4605 mL | 1.1513 mL | |
| 60 mM | 0.0384 mL | 0.1919 mL | 0.3838 mL | 0.9594 mL | |
| 80 mM | 0.0288 mL | 0.1439 mL | 0.2878 mL | 0.7196 mL | |
| 100 mM | 0.0230 mL | 0.1151 mL | 0.2303 mL | 0.5757 mL |