Cytembena
Based on 1 Customer Validation
Cytembena is inhibitor for replicative DNA synthesis, purine synthesis and tetrahydrofolate formylase activity. Cytembena ameliorates ovarian or breast cancer, relieves the pain from skeletal metastases.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.53%
- No. CAS: 21739-91-3
- Fòrmula: C11H8BrNaO4
- Peso molecular:307.07
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Almacenamiento:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Chemical Information
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No. CAS 21739-91-3
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Appearance Solid
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Peso molecular 307.07
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Fòrmula C11H8BrNaO4
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Color Light yellow to yellow
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SMILES
O=C(O[Na])/C=C(Br)\C(C1=CC=C(C=C1)OC)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvente y solubilidad
DMSO : 50 mg/mL (162.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Falkson HC, et al., Phase II trial of cytembena in patients with advanced ovarian and breast cancer. Cancer Treat Rep. 1976 Nov;60(11):1655-8. [Content Brief]
[2]. Berger NA, et al., Description of a permeable eukaryotic cell system to study agents affecting DNA synthesis: demonstration that cytembena is a direct inhibitor of replicative DNA synthesis. J Natl Cancer Inst. 1977 Apr;58(4):1167-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2566 mL | 16.2829 mL | 32.5659 mL | 81.4147 mL |
| 5 mM | 0.6513 mL | 3.2566 mL | 6.5132 mL | 16.2829 mL | |
| 10 mM | 0.3257 mL | 1.6283 mL | 3.2566 mL | 8.1415 mL | |
| 15 mM | 0.2171 mL | 1.0855 mL | 2.1711 mL | 5.4276 mL | |
| 20 mM | 0.1628 mL | 0.8141 mL | 1.6283 mL | 4.0707 mL | |
| 25 mM | 0.1303 mL | 0.6513 mL | 1.3026 mL | 3.2566 mL | |
| 30 mM | 0.1086 mL | 0.5428 mL | 1.0855 mL | 2.7138 mL | |
| 40 mM | 0.0814 mL | 0.4071 mL | 0.8141 mL | 2.0354 mL | |
| 50 mM | 0.0651 mL | 0.3257 mL | 0.6513 mL | 1.6283 mL | |
| 60 mM | 0.0543 mL | 0.2714 mL | 0.5428 mL | 1.3569 mL | |
| 80 mM | 0.0407 mL | 0.2035 mL | 0.4071 mL | 1.0177 mL | |
| 100 mM | 0.0326 mL | 0.1628 mL | 0.3257 mL | 0.8141 mL |
Cytembena Related Classifications
HY-129246 Related Classifications
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