F3 peptide
F3 peptide is a nucleolin-binding tumor-homing peptide that mediates selective uptake and internalization by tumor cells. F3 peptide is a 31-amino acid fragment of human high mobility group nucleosomal protein 2 (HMGN2). F3 peptide inhibits protein synthesis through ribosome inactivation. F3 peptide targets the tumor vasculature. F3 peptide can serve as an effective ligand to improve the druggability of macromolecular drugs or nanoparticles. F3 peptide is used in research on cancers such as glioblastoma and breast cancer.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 536971-53-6
- Fòrmula: C152H263N49O41
- Peso molecular:3433.02
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas DNA/RNA Synthesis
More
Actividad biológica
Descripciòn
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:MDA-MB-231-H2N (231-H2N) human breast cancer cells
-
Concentration:10 nM
-
Incubation Time:2 h
-
Result:Showed membrane-bound and internalized fluorescence.
Observed in the nuclei, where it co-localized with nucleolin in the nucleoli.
Nuclear localization was approximately 33.6% of the total amount internalized.
Chemical Information
-
No. CAS 536971-53-6
-
Peso molecular 3433.02
-
Fòrmula C152H263N49O41
-
Sequence
Lys-Asp-Glu-Pro-Gln-Arg-Arg-Ser-Ala-Arg-Leu-Ser-Ala-Lys-Pro-Ala-Pro-Pro-Lys-Pro-Glu-Pro-Lys-Pro-Lys-Lys-Ala-Pro-Ala-Lys-Lys
-
Sequence Shortening
KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)