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Referencia número: HY-182474

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INDOPY-1

Name: INDOPY-1
Brand: MedChemExpress
SKU: HY-182474
Availability: PreOrder

(Synonyms: Indolopyridone-1)

INDOPY-1 (Indolopyridone-1) is a selective, reversible, and competitive HIV-1 reverse transcriptase inhibitor. INDOPY-1 reversibly binds to the active site of reverse transcriptase. INDOPY-1 inhibits DNA synthesis. INDOPY-1 exhibits antiviral activity against various retroviruses, including HIV-1 IIIB, HIV-1 HXB2 K103N Y181C, HIV-2 ROD, and SIV Mac251. INDOPY-1 can be used in the research of immunodeficiency virus infection.

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No. CAS: 352548-47-1
Fòrmula: C₁₉H₁₂N₄O₃
Peso molecular:344.32

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

INDOPY-1 Chemical Structure

No. CAS: 352548-47-1

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- IC₅₀ & Target
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Actividad biológica

Descripciòn

IC₅₀ & Target

^[1]

HIV-1

HIV-2

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In Vitro

INDOPY-1 inhibits DNA synthesis, with an IC₅₀ of 0.29 μM measured using Poly (rA) · poly (dT) and an IC₅₀ of 1.1 μM measured using Poly (rI) · poly (dC)^[1].
INDOPY-1 exhibits antiviral activity against diverse retroviruses, including HIV-1 IIIB, HIV-1 HXB2 K103N Y181C, HIV-2 ROD, and SIV Mac251^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 352548-47-1
Peso molecular 344.32
Fòrmula C₁₉H₁₂N₄O₃
SMILES

N#CC(C(N1C2=CC=C([N+]([O-])=O)C=C2)=O)=CC(N3C)=C1C4=C3C=CC=C4
Synonyms

Indolopyridone-1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Jochmans D, et al. Indolopyridones inhibit human immunodeficiency virus reverse transcriptase with a novel mechanism of action. J Virol. 2006;80(24):12283-12292. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureza y Documentación
Referencias

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INDOPY-1

Ver todos los productos específicos de isoformas DNA/RNA Synthesis

Ver todos los productos específicos de isoformas HIV