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Referencia número: HY-160991

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Menabitan

(Synonyms: SP-204)

Menabitan (SP-204) is an inhibitor for phosphodiesterase 9 (PDE 9), which acts as a non-opioid analgesic agent. Menabitan lowers the intraocular pressure in rabbit model.

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No. CAS: 83784-21-8
Fòrmula: C₃₇H₅₆N₂O₃
Peso molecular:576.85

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Menabitan Chemical Structure

No. CAS: 83784-21-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- IC₅₀ & Target
Chemical Information
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Actividad biológica

Descripciòn

Menabitan (SP-204) is an inhibitor for phosphodiesterase 9 (PDE 9), which acts as a non-opioid analgesic agent. Menabitan lowers the intraocular pressure in rabbit model^[1].

IC₅₀ & Target

PDE9

Ver todos los productos específicos de isoformas Phosphodiesterase (PDE) :

Chemical Information

No. CAS 83784-21-8
Peso molecular 576.85
Fòrmula C₃₇H₅₆N₂O₃
SMILES

O=C(C(CCN1CCCCC1C)C)OC2=CC(C(C(CCCCC)C)C)=CC3=C2C(CN(CC4)CC#C)=C4C(C)(C)O3
Synonyms

SP-204
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Anaebonam A O. Analytical, formulation development and stability testing of a lyophilized dosage form of menabitan hydrochloride, a new potent analgesic[M]. Massachusetts College of Pharmacy and Health Sciences, 1986.

[2]. PITTENGER C, et al., Enhancement of the efficacy of serotonergic psychedelic drugs in the treatment or prevention of certain neuropsychiatric disorders through inhibition of type-9 phosphodiesterases. WO2024107445.

[3]. Green K, et al., Acute dose response of intraocular pressure to topical and oral cannabinoids. Proc Soc Exp Biol Med. 1977 Feb;154(2):228-31. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Menabitan

Ver todos los productos específicos de isoformas Phosphodiesterase (PDE)

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Menabitan Related Classifications

HY-160991 Related Classifications