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PY159

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Based on 1 Customer Validation

PY159 is a humanized antibody targeting TREM1/CD354. PY159 reprograms immunosuppressive intratumoral myeloid cells towards an inflammatory, anti-tumor phenotype, promotes anti-tumor immune responses, upregulates monocyte activation markers, and induces proinflammatory cytokines. PY159 can be used for the research of platinum-resistant ovarian cancer, advanced solid tumors, and advanced refractory solid tumors.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza: 98.44%
  • Peso molecular:143.66 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for PY159
  • Experimental Validation Results for PY159
  • PY159 Chemical Structure
    PY159 Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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PY159 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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100 mg

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  • 1/16

    Flow Cytometry analysis of HL-60 cells labelling PY159 (red) with PY159 (anti-TREM-1/CD354) (HY-P990650). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001).

  • 1/16

    Immobilized TREM-1 Protein, Human can bind PY159. The EC50 for this effect is 6.183 ng/mL.

  • PY159 Chemical Structure
    1/16
  • PY159
  • Flow Cytometry analysis of HL-60 cells labelling PY159 (red) with PY159 (anti-TREM-1/CD354) (HY-P990650). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001).
  • Immobilized TREM-1 Protein, Human can bind PY159. The EC50 for this effect is 6.183 ng/mL.