TB-11
Based on 1 Customer Validation
TB-11 is a Cathepsin D inhibitor, with IC50s of 0.126 nM (Cathepsin D), 1.92 nM (Cathepsin E), 48.8 nM (BACE1), respectively. TB-11 can be used for tumor research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 98.71%
- No. CAS: 1415033-93-0
- Fòrmula: C52H78N8O12
- Peso molecular:1007.22
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Almacenamiento:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Ver todos los productos específicos de isoformas Cathepsin
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Actividad biológica
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Cathepsin D 0.126 nM (IC50) |
Cathepsin E 1.92 nM (IC50) |
BACE1 48.8 nM (IC50) |
Chemical Information
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No. CAS 1415033-93-0
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Appearance Solid
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Peso molecular 1007.22
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Fòrmula C52H78N8O12
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Color White to off-white
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SMILES
CC(C)(C)OC(N[C@@H](C(C)C)C(N(C)[C@@H](CCC(N)=O)C(N[C@@H](CC1=CC=CC=C1)[C@@H](O)CC(N[C@@H](CC(C)C)C(N[C@@H](C)C(N(C)[C@H](CC2=CC=CC=C2)C(N3[C@@H](CCC3)C(OC)=O)=O)=O)=O)=O)=O)=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvente y solubilidad
DMSO : 100 mg/mL (99.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9928 mL | 4.9642 mL | 9.9283 mL | 24.8208 mL |
| 5 mM | 0.1986 mL | 0.9928 mL | 1.9857 mL | 4.9642 mL | |
| 10 mM | 0.0993 mL | 0.4964 mL | 0.9928 mL | 2.4821 mL | |
| 15 mM | 0.0662 mL | 0.3309 mL | 0.6619 mL | 1.6547 mL | |
| 20 mM | 0.0496 mL | 0.2482 mL | 0.4964 mL | 1.2410 mL | |
| 25 mM | 0.0397 mL | 0.1986 mL | 0.3971 mL | 0.9928 mL | |
| 30 mM | 0.0331 mL | 0.1655 mL | 0.3309 mL | 0.8274 mL | |
| 40 mM | 0.0248 mL | 0.1241 mL | 0.2482 mL | 0.6205 mL | |
| 50 mM | 0.0199 mL | 0.0993 mL | 0.1986 mL | 0.4964 mL | |
| 60 mM | 0.0165 mL | 0.0827 mL | 0.1655 mL | 0.4137 mL | |
| 80 mM | 0.0124 mL | 0.0621 mL | 0.1241 mL | 0.3103 mL |
TB-11 Related Classifications
HY-164958 Related Classifications
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