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Vantictumab

(Synonyms: OMP-18R5)
1 Cited Publications
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Based on 1 publication(s) in Google Scholar

Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to FZD1/2/5/7/8 receptors. Vantictumab can be studied against cancers through direct actions on tumor cells, including CSCs, and effects on the stroma, such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza: 99.00%
  • No. CAS: 1345009-45-1
  • Peso molecular:143.16 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Vantictumab
  • Experimental Validation Results for Vantictumab
  • Vantictumab Chemical Structure
    Vantictumab Chemical Structure
No. CAS: 1345009-45-1
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Vantictumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG2 lambda

  • 1/16

    Loaded Vantictumab on AHC2 biosensor, can bind Frizzled-8 Protein, Human (HEK293, His, HY-P70915) with an affinity constant of 1.183E-07 M as determined in BLI assay.

  • Vantictumab Chemical Structure
    1/16
  • Vantictumab
  • Loaded Vantictumab on AHC2 biosensor, can bind Frizzled-8 Protein, Human (HEK293, His, HY-P70915) with an affinity constant of 1.183E-07 M as determined in BLI assay.