VU0463841
VU0463841 is a potent, selective and brain-penetrant mGlu5 negative allosteric modulator (NAM) with an IC50 of 13 nM. VU0463841 is ineffective against mGlu1-4 and mGlu7-8. VU0463841 has the potential for the Cocaine addiction research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1439095-16-5
- Fòrmula: C13H8ClFN4O
- Peso molecular:290.68
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
- Protocolo
- Pureza y Documentación
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
mGlu5 Receptor 13 nM (IC50) |
Chemical Information
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No. CAS 1439095-16-5
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Peso molecular 290.68
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Fòrmula C13H8ClFN4O
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SMILES
O=C(NC1=NC=C(C=C1)Cl)NC2=CC(F)=CC(C#N)=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VU0463841 Related Classifications
HY-120527 Related Classifications
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