1. Gene
  2. IP6K3 - inositol hexakisphosphate kinase 3 Gene

IP6K3 - inositol hexakisphosphate kinase 3 Gene

Homo sapiens

Also known as IHPK3; INSP6K3

Gene ID: 117283 | Gene type: protein coding

About IP6K3

Cytogenetic location: 6p21.31 Genomic coordinates (GRCh38): 6:33,721,662-33,762,145 (from NCBI)

This gene has 3 transcripts (splice variants), 138 orthologues and 6 paralogues. Broad expression in thyroid (RPKM 4.4), heart (RPKM 3.1) and 14 other tissues.

Summary

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008]

IP6K3 Products(2)

mRNA Protein Name
NM_001142883.2 NP_001136355.1 inositol hexakisphosphate kinase 3
NM_054111.5 NP_473452.2 inositol hexakisphosphate kinase 3

IP6K3 Protein Structure

IPK

IPK: Inositol polyphosphate kinase (198 - 404)

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  • 410 a.a.
Protein Preferred Names Protein Names

inositol hexakisphosphate kinase 3

ATP:1D-myo-inositol-hexakisphosphate phosphotransferase

Orthologs Information

Species Symbol Source ID
Bos taurus IP6K3 VGNC VGNC:107290
Mus musculus IP6K3 MGD MGI:3045325
Felis catus IP6K3 VGNC VGNC:102444
Canis familiaris IP6K3 VGNC VGNC:42063
Macaca mulatta IP6K3 VGNC VGNC:81083
Rattus norvegicus IP6K3 RGD RGD:1584104