Dcn - decorin Gene

Also Known as DC; PG40; PGII; PGS2; DSPG2; SLRR1B

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13179

Summary

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate a mature protein product, which is secreted into the extracellular space to regulate Collagen fibril assembly. Homozygous knockout mice for this gene exhibit enhanced tumorigenesis in a liver Cancer model, and defects in Collagen fibrils, leading to weakened skin and tendons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Dcn Products (2)

mRNA Protein Name
NM_001190451.2 NP_001177380.1 decorin preproprotein
NM_007833.6 NP_031859.1 decorin preproprotein

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables extracellular matrix binding IDA
IDA: Inferred from direct assay
18757743 MGI
enables glycosaminoglycan binding IDA
IDA: Inferred from direct assay
18757743 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

decorin

  • bone proteoglycan II

Recombinant Dcn Proteins

Cat. No. Product Name Accession Purity
HY-P70021 Decorin/PGS2 Protein, Mouse (HEK293, His) P28654 (G17-K354) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (21)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-124602 DI-591 Inhibitor 98.36% Unkown
HY-145733 DI-1859 99.62% Unkown
HY-111505 NAcM-OPT Inhibitor 98.69% Unkown
HY-W264347 DCN1-UBC12-IN-4 Inhibitor 95.10% Unkown
HY-126075A WS-383 Inhibitor 99.43% Unkown
HY-161470 WS-384 98.23% Unkown
HY-126075 WS-383 free base Inhibitor / Unkown
HY-122874 DI-404 Inhibitor / Unkown
HY-142691 DCN1-UBC12-IN-1 Inhibitor / Unkown
HY-142692 DCN1-UBC12-IN-3 Inhibitor / Unkown
HY-142694 DCN1-UBC12-IN-2 Inhibitor / Unkown
HY-149980 DCN-83 Inhibitor / Unkown
HY-156240 DI-1548 / Unkown
HY-163014 Dicamba 1-azidopropane / Unkown
HY-169026 DCN1-IN-2 Inhibitor / Unkown
HY-184536 DCN1 modulator-1 Modulator / Unkown
HY-RS03583 DCN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-111505A NAcM-OPT hydrochloride Inducer / Unkown
HY-151794 DACN(Ms) hydrochloride / Unkown
HY-RS17215 Dcn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23667 Dcn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dcn NCBI NCBI:1634