Ulk2 - unc-51 like autophagy activating kinase 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding

Gene ID: 303206

About Ulk2

Primary_assembly 10: 46,454,030-46,530,407 reverse strand.mRatBN7.2:CM026983.1

This gene has 3 transcripts (splice variants), 206 orthologues, 2 paralogues and is associated with 4 phenotypes. Biased expression in Muscle (RPKM 159.8), Lung (RPKM 151.5) and 9 other tissues.

Summary

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including Autophagy of nucleus; macroautophagy; and protein phosphorylation. Predicted to be active in phagophore assembly site membrane. Orthologous to human ULK2 (unc-51 like Autophagy activating kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ulk2 Products (1)

mRNA	Protein	Name
NM_001191645.2	NP_001178574.1	serine/threonine-protein kinase ULK2

Ulk2 Protein Structure

STKc_ULK2

DUF3543

0
200
400
600
800
1000
1059 a.a.

Protein Preferred Names	Protein Names
serine/threonine-protein kinase ULK2	Unc-51 like kinase 2

Related Agents

Clinical Phase
Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-160699	DCC-3116	Inhibitor	99.84%	Phase 2

Pre-clinical Phase

Bioactive Molecules (12)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-16966	SBI-0206965	Inhibitor	99.92%	Unkown
HY-13018	MRT67307	Inhibitor	99.56%	Unkown
HY-100006	MRT68921	Inhibitor	98.09%	Unkown
HY-114490	ULK-101	Inhibitor	99.91%	Unkown
HY-100006A	MRT68921 dihydrochloride	Inhibitor	99.67%	Unkown
HY-137742	SBP-7455	Inhibitor	98.01%	Unkown
HY-179089	SBP-1750	Inhibitor	98.05%	Unkown
HY-13018A	MRT67307 hydrochloride	Inhibitor	/	Unkown
HY-162100	MR-2088	Inhibitor	99.50%	Unkown
HY-181742	ULK1/2-IN-1	Inhibitor	/	Unkown
HY-181815	SBP-5147	Inhibitor	/	Unkown
HY-100006B	MRT68921 hydrochloride	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ulk2	NCBI	NCBI:9706