ZNF580 - zinc finger protein 580 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51157

Summary

Enables sequence-specific double-stranded DNA binding activity. Involved in several processes, including cellular response to hydrogen peroxide; positive regulation of cell migration; and positive regulation of interleukin-8 production. Located in nucleus. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in fat (RPKM 10.9), prostate (RPKM 9.2) and 25 other tissues.

ZNF580 Products (3)

mRNA Protein Name
NM_001163423.2 NP_001156895.1 zinc finger protein 580
NM_016202.2 NP_057286.1 zinc finger protein 580
NM_207115.2 NP_996998.1 zinc finger protein 580

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21599657 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
Biological Process GO Annotation Evidence References Source
involved in cellular response to hydrogen peroxide IDA
IDA: Inferred from direct assay
21830064 GOA
involved in positive regulation of endothelial cell migration IDA
IDA: Inferred from direct assay
20382120 GOA
involved in positive regulation of endothelial cell proliferation IDA
IDA: Inferred from direct assay
20382120 GOA
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
20382120 GOA
involved in positive regulation of interleukin-8 production IDA
IDA: Inferred from direct assay
21830064 GOA
involved in positive regulation of leukocyte chemotaxis IDA
IDA: Inferred from direct assay
21830064 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
20382120 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF580 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF580 Q9UK33 KRT40 Homo sapiens Q6A162
Y2H Array
32296183
Intra
ZNF580 Q9UK33 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra
ZNF580 Q9UK33 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 KRTAP10-7 Homo sapiens P60409
Y2H Array
32296183
Intra
ZNF580 Q9UK33 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
ZNF580 Q9UK33 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 PSTPIP1 Homo sapiens O43586
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 PSTPIP1 Homo sapiens O43586
Y2H Array
32296183
Intra
ZNF580 Q9UK33 IKZF1 Homo sapiens Q13422-7
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 IKZF1 Homo sapiens Q13422-7
Y2H Array
32296183
Intra
ZNF580 Q9UK33 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra
ZNF580 Q9UK33 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 BANP Homo sapiens Q8N9N5-2
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 BANP Homo sapiens Q8N9N5-2
Y2H Array
32296183
Intra
ZNF580 Q9UK33 NOTCH2NLC Homo sapiens P0DPK4
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 NOTCH2NLC Homo sapiens P0DPK4
Y2H Array
32296183
Intra
ZNF580 Q9UK33 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
Intra
ZNF580 Q9UK33 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
ZNF580 Q9UK33 FSD2 Homo sapiens A1L4K1
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 FSD2 Homo sapiens A1L4K1
Y2H Array
32296183
Intra
ZNF580 Q9UK33 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
ZNF580 Q9UK33 TRIM27 Homo sapiens P14373
Y2H Array
32296183
Intra
ZNF580 Q9UK33 TRIM27 Homo sapiens P14373
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 KHDRBS3 Homo sapiens O75525
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 KHDRBS3 Homo sapiens O75525
Y2H Array
32296183
Intra
ZNF580 Q9UK33 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra
ZNF580 Q9UK33 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 TRIP6 Homo sapiens Q15654
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 TRIP6 Homo sapiens Q15654
Y2H Array
32296183
Intra
ZNF580 Q9UK33 ZNF436 Homo sapiens Q9C0F3
Y2H Prey Pooling
32296183
Intra
ZNF580 Q9UK33 ZNF436 Homo sapiens Q9C0F3
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16154 ZNF582 Human Pre-designed siRNA Set A Pre-designed Set / Unkown