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No matches for "

55195

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11

Inhibitors & Agonists

4

Antibodies

8

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-167868
    DWP-05195

    		TRP Channel Apoptosis Neurological Disease Cancer
    DWP-05195 is a TRPV1 antagonist that can inhibit the pain signal transduction. DWP-05195 induces ER stress-dependent apoptosis through the ROS-p38-CHOP pathway in human ovarian cancer cells .
    DWP-05195
  • HY-107696
    Ro 04-5595 hydrochloride

    		iGluR Neurological Disease
    Ro 04-5595 hydrochloride is a GluN2B-selective NMDA receptor antagonist (Ki: 31 nM) .
    Ro 04-5595 hydrochloride
  • HY-136659
    Ro 04-5595

    		iGluR Others
    Ro 04-5595 is a selective antagonist with specific activity against the NR2B subunit of the NMDA receptor. Ro 04-5595 exhibits favorable pharmacokinetic properties in in vitro and in vivo studies, with rapid uptake and clearance. Ro 04-5595 exhibits strong binding in NR2B receptor-enriched regions and low binding in the cerebellum. Ro 04-5595 is able to effectively inhibit specific binding, showing high affinity for the NR2B receptor and a clear ranking of binding affinity with a variety of other compounds .
    Ro 04-5595
  • HY-R01582
    hsa-miR-5195-5p mimic

    		MicroRNA Cancer
    hsa-miR-5195-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-5195-5p mimic
    hsa-miR-5195-5p mimic
  • HY-R01581A
    hsa-miR-5195-3p agomir

    		MicroRNA Cancer
    hsa-miR-5195-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-5195-3p agomir
    hsa-miR-5195-3p agomir
  • HY-RI01582A
    hsa-miR-5195-5p antagomir

    		MicroRNA Cancer
    hsa-miR-5195-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-5195-5p antagomir
    hsa-miR-5195-5p antagomir
  • HY-RI01581A
    hsa-miR-5195-3p antagomir

    		MicroRNA Cancer
    hsa-miR-5195-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-5195-3p antagomir
    hsa-miR-5195-3p antagomir
  • HY-R01581
    hsa-miR-5195-3p mimic

    		MicroRNA Cancer
    hsa-miR-5195-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-5195-3p mimic
    hsa-miR-5195-3p mimic
  • HY-RI01582
    hsa-miR-5195-5p inhibitor

    		MicroRNA Cancer
    hsa-miR-5195-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-5195-5p inhibitor
    hsa-miR-5195-5p inhibitor
  • HY-R01582A
    hsa-miR-5195-5p agomir

    		MicroRNA Cancer
    hsa-miR-5195-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-5195-5p agomir
    hsa-miR-5195-5p agomir
  • HY-RI01581
    hsa-miR-5195-3p inhibitor

    		MicroRNA Cancer
    hsa-miR-5195-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-5195-3p inhibitor
    hsa-miR-5195-3p inhibitor

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