2. Gene
  3. TNRC6C - trinucleotide repeat containing adaptor 6C Gene

TNRC6C - trinucleotide repeat containing adaptor 6C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 57690 | Gene type: protein coding

About TNRC6C

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:77,957,557-78,108,835 (from NCBI)

This gene has 11 transcripts (splice variants), 198 orthologues and 5 paralogues. Ubiquitous expression in brain (RPKM 4.2), testis (RPKM 3.1) and 25 other tissues.

Summary

Predicted to enable RNA binding activity. Involved in gene silencing by miRNA; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; and positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Predicted to be located in cytosol. Predicted to be active in P-body and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TNRC6C Products(7)

mRNA Protein Name
NM_001142640.2 NP_001136112.2 trinucleotide repeat-containing gene 6C protein isoform 1
NM_001395508.1 NP_001382437.1 trinucleotide repeat-containing gene 6C protein isoform 3
NM_001395509.1 NP_001382438.1 trinucleotide repeat-containing gene 6C protein isoform 4
NM_001395510.1 NP_001382439.1 trinucleotide repeat-containing gene 6C protein isoform 5
NM_001395511.1 NP_001382440.1 trinucleotide repeat-containing gene 6C protein isoform 6
NM_001395512.1 NP_001382441.1 trinucleotide repeat-containing gene 6C protein isoform 7
NM_018996.3 NP_061869.2 trinucleotide repeat-containing gene 6C protein isoform 2

TNRC6C Protein Structure

Ago_hook

Ago_hook: Argonaute hook (818 - 942)

UBA

UBA: UBA/TS-N domain (943 - 973)

M_domain

M_domain: M domain of GW182 (991 - 1249)

RRM_5

RRM_5: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (1530 - 1584)

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  • 1690 a.a.
Protein Preferred Names Protein Names

trinucleotide repeat-containing gene 6C protein

trinucleotide repeat containing 6C

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14866 TNRC6C Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TNRC6C VGNC VGNC:47700
Rattus norvegicus TNRC6C RGD RGD:1310027
Macaca mulatta TNRC6C VGNC VGNC:79800
Mus musculus TNRC6C MGD MGI:2443265
Bos taurus TNRC6C VGNC VGNC:36206
Felis catus TNRC6C VGNC VGNC:99564