HDAC4 - histone deacetylase 4 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 607662

About HDAC4

Primary_assembly 25: 49,706,181-49,977,414 reverse strand.ROS_Cfam_1.0:CM025124.1

This gene has 2 transcripts (splice variants), 263 orthologues and 10 paralogues.

HDAC4 Products (16)

mRNA Protein Name
XM_038435960.1 XP_038291888.1 histone deacetylase 4 isoform X4
XM_038435959.1 XP_038291887.1 histone deacetylase 4 isoform X3
XM_038435962.1 XP_038291890.1 histone deacetylase 4 isoform X6
XM_038435958.1 XP_038291886.1 histone deacetylase 4 isoform X2
XM_038435963.1 XP_038291891.1 histone deacetylase 4 isoform X7
XM_038435964.1 XP_038291892.1 histone deacetylase 4 isoform X8
XM_038435961.1 XP_038291889.1 histone deacetylase 4 isoform X5
XM_038435957.1 XP_038291885.1 histone deacetylase 4 isoform X1
XM_038435961.1 XP_038291889.1 histone deacetylase 4 isoform X5
XM_038435960.1 XP_038291888.1 histone deacetylase 4 isoform X4
XM_038435962.1 XP_038291890.1 histone deacetylase 4 isoform X6
XM_038435963.1 XP_038291891.1 histone deacetylase 4 isoform X7
XM_038435958.1 XP_038291886.1 histone deacetylase 4 isoform X2
XM_038435959.1 XP_038291887.1 histone deacetylase 4 isoform X3
XM_038435957.1 XP_038291885.1 histone deacetylase 4 isoform X1
XM_038435964.1 XP_038291892.1 histone deacetylase 4 isoform X8

HDAC4 Protein Structure

ClassIIa_HDAC4_Gln-rich-N

ClassIIa_HDAC4_Gln-rich-N: cd10162 (94 - 158)

HDAC4

HDAC4: cd10006 (654 - 1062)

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  • 1000
  • 1090 a.a.
Protein Preferred Names Protein Names

histone deacetylase 4

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (5)
Art. -Nr. Produktname Wirkung
Reinheit Rare Diseases
HY-15149 Romidepsin Inhibitor 99.98% Unkown
HY-14842 Givinostat Inhibitor 98.67% Yes
HY-13322 Pracinostat Inhibitor 99.80% Yes
HY-14842B Givinostat hydrochloride monohydrate Inhibitor 99.63% Yes
HY-14842A Givinostat hydrochloride Inhibitor 98.06% Yes

Clinical Phase

Bioactive Molecules (6)
Art. -Nr. Produktname Wirkung
Reinheit Phase
HY-10528 Tasquinimod Modulator 99.70% Phase 3
HY-16026 Ricolinostat Inhibitor 99.83% Phase 2
HY-15433 Quisinostat Inhibitor 99.71% Phase 2
HY-13522 Fimepinostat Inhibitor 99.95% Phase 2
HY-15433A Quisinostat dihydrochloride Inhibitor 99.05% Phase 2
HY-10223 CUDC-101 Inhibitor 99.05% Phase 1

Pre-clinical Phase

Bioactive Molecules (60)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-18361 TMP195 Inhibitor 99.82% Unkown
HY-13428 Tubacin Inhibitor 97.11% Unkown
HY-18998 LMK-235 Inhibitor 99.61% Unkown
HY-18360 TMP269 Inhibitor 98.16% Unkown
HY-16699 Nexturastat A Inhibitor 98.69% Unkown
HY-19350 BML-210 Inhibitor 98.04% Unkown
HY-119939 CHDI-390576 Inhibitor 98.10% Unkown
HY-115475 SW-100 Inhibitor 99.93% Unkown
HY-123295 HDAC3-IN-T247 Inhibitor 98.91% Unkown
HY-169259 HDAC9-IN-1 Inhibitor 95.13% Unkown
HY-150109 Purinostat mesylate Inhibitor 99.45% Unkown
HY-135714 Bavarostat Inhibitor 99.51% Unkown
HY-149285 NT160 Inhibitor 99.58% Unkown
HY-W039803 HDAC4 ligand-2 Ligand / Unkown
HY-146153 HDAC-IN-40 Inhibitor 98.71% Unkown
HY-12954 PTACH Inhibitor 99.65% Unkown
HY-149721 HDAC4-IN-1 Inhibitor 98.11% Unkown
HY-148624 CHDI-00484077 Inhibitor 98.38% Unkown
HY-149208 HDAC-IN-53 Inhibitor 95.73% Unkown
HY-184524 PROTAC HDAC4 Degrader-2 / Unkown
HY-157740 XSJ-10 Inhibitor 95.16% Unkown
HY-117554 BRD9757 Inhibitor 99.75% Unkown
HY-146678 HDAC6-IN-5 Inhibitor / Unkown
HY-146679 HDAC6-IN-6 Inhibitor / Unkown
HY-179321 PROTAC HDAC4 Degrader-1 Degrader / Unkown
HY-161778 ZG-126 Inhibitor / Unkown
HY-150595 HDAC6-IN-10 Inhibitor / Unkown
HY-178022 HDAC6-IN-63 Inhibitor / Unkown
HY-151896 HDAC6-IN-14 Inhibitor / Unkown
HY-151263 G4/HDAC-IN-1 Inhibitor / Unkown
HY-149372 HDAC6-IN-17 Inhibitor / Unkown
HY-146159 PI3K/HDAC-IN-2 Inhibitor / Unkown
HY-150503 KH-259 Inhibitor / Unkown
HY-163803 CM-444 Inhibitor / Unkown
HY-175030 TNI-97 Inhibitor / Unkown
HY-176868 Rodin-C Inhibitor / Unkown
HY-146684 HDAC-IN-36 Inhibitor / Unkown
HY-152225 MC2625 Inhibitor / Unkown
HY-170379 HDAC-IN-84 Inhibitor / Unkown
HY-162630 HDAC6-IN-44 Inhibitor / Unkown
HY-163143 HDAC8-IN-6 Inhibitor / Unkown
HY-151897 HDAC-IN-49 Inhibitor / Unkown
HY-152226 MC2590 Inhibitor 98.71% Unkown
HY-181086 FLT3/HDAC-IN-3 Inhibitor / Unkown
HY-184203 SM-06-09 Inhibitor / Unkown
HY-15144B (S)-Trichostatin A Inhibitor / Unkown
HY-143233 PIM-1/HDAC-IN-1 Inhibitor / Unkown
HY-169400 HDACs/EZH2-IN-1 Inhibitor / Unkown
HY-174302 PIM-1/HDAC-IN-2 Inhibitor / Unkown
HY-172159 FF2039 Inhibitor / Unkown
HY-147934 HDAC8-IN-3 Inhibitor / Unkown
HY-183560 HDAC6-IN-82 Inhibitor / Unkown
HY-181579 HDAC6-IN-74 Inhibitor / Unkown
HY-124946 C1A Inhibitor / Unkown
HY-149283 JAK/HDAC-IN-2 Inhibitor / Unkown
HY-15433B Quisinostat hydrochloride Inhibitor / Unkown
HY-180214 HDAC6-IN-69 Inhibitor / Unkown
HY-179227 HDAC6 ligand-7 Inhibitor / Unkown
HY-182747 HDAC6-IN-79 Inhibitor / Unkown
HY-P2044 Azumamide E Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens HDAC4 NCBI NCBI:9759