NRIP1 - nuclear receptor interacting protein 1 Gene

Homo sapiens

Also known as CAKUT3; RIP140

Gene ID: 8204 | Gene type: protein coding

About NRIP1

Cytogenetic location: 21q11.2-q21.1 Genomic coordinates (GRCh38): 21:14,961,235-15,065,936 (from NCBI)

This gene has 7 transcripts (splice variants) and 197 orthologues. Ubiquitous expression in fat (RPKM 19.2), endometrium (RPKM 12.9) and 25 other tissues.

Summary

Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein modulates transcriptional activity of the Estrogen Receptor. [provided by RefSeq, Jul 2008]

NRIP1 Products(1)

mRNA	Protein	Name
NM_003489.4	NP_003480.2	nuclear receptor-interacting protein 1

Protein Preferred Names

Protein Names

nuclear receptor-interacting protein 1

nuclear factor RIP140

Related Diseases

Diseases

Alias

Congenital Anomalies Of Kidney And Urinary Tract 3

CAKUT3

Cakut

Renal Or Urinary Tract Malformation	Congenital Anomalies Of Kidney And Urinary Tract
Congenital Anomaly Of Kidney And Urinary Tract	Congenital Anomalies Of The Kidney And Urinary Tract
Kidney And Urinary Tract, Anomalies, Congenital	Renal Hypodysplasia, Nonsyndromic, 1

Posterior Urethral Valves

Posterior Urethral Valve	Congenital Posterior Urethral Valves
Puv

Embryonal Carcinoma

Embryonal Neoplasm	Embryonal Cancer
Primary Extragonadal Embryonal Carcinoma	Embryo Neoplasm
Carcinoma Embryonal	Cancer Embryonal
Carcinoma, Embryonal	Extragonadal Embryonal Carcinoma
Cancer, Embryonal

Infertility

Down Syndrome

Trisomy 21	Complete Trisomy 21 Syndrome
Down'S Syndrome	Trisomy 21 Syndrome
Down'S Syndrome - Trisomy 21	Downs Syndrome
G Trisomy	47,Xx,+21
47,Xy,+21	Trisomy G
Down Syndrome, Susceptibility To	Chromosome 21 Trisomy
Trisomy 21 Nos	Abnormal Autosomes 21

Chronic Kidney Disease

Chronic Renal Disease	Chronic Kidney Failure
Ckd	Chronic Renal Failure
Kidney Failure, Chronic	Chronic Renal Failure Syndrome
Crf	Renal Failure - Chronic
Renal Failure Chronic	Chronic Kidney Diseases
Chronic Kidney Disease Stage 5	Ckd - [Chronic Kidney Disease]
Crf - [Chronic Renal Failure]	Chronic Kidney Impairment
Chronic Renal Impairment	Chronic Kidney Shutdown
Chronic Hypoxic Kidney Failure	Chronic Kidney Collapse
Chronic Renal Insufficiency	Chronic Kidney Toxaemia
Chronic Kidney Hypofunction	Chronic Renal Suppression
Chronic Renal Failure, Stage 5	Ckd - [Chronic Kidney Disease] Stage 5
End Stage Kidney Failure	End Stage Renal Failure
End Stage Kidney Disease	End Stage Renal Disease
End Stage Chronic Renal Failure	Esrf - [End Stage Renal Failure]
Esrd - [End Stage Renal Diseases]	Egfr - [Estimated Glomerular Filtration Rate] < 15 Ml/Min/1.73m²

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09571	NRIP1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	NRIP1	VGNC	VGNC:43969
Bos taurus	NRIP1	VGNC	VGNC:32263
Mus musculus	NRIP1	MGD	MGI:1315213
Rattus norvegicus	NRIP1	RGD	RGD:1311850
Felis catus	NRIP1	VGNC	VGNC:68567
Macaca mulatta	NRIP1	VGNC	VGNC:75529

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