2. Gene
  3. PARP10 - poly(ADP-ribose) polymerase family member 10 Gene

PARP10 - poly(ADP-ribose) polymerase family member 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as ARTD10

Gene ID: 84875 | Gene type: protein coding

About PARP10

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:143,977,158-144,012,764 (from NCBI)

This gene has 23 transcripts (splice variants), 204 orthologues and 8 paralogues. Ubiquitous expression in spleen (RPKM 25.6), lymph node (RPKM 16.2) and 25 other tissues.

Summary

Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005 [PubMed 15674325]).[supplied by OMIM, Mar 2008]

PARP10 Products(6)

mRNA Protein Name
NR_134234.2
XM_011517336.4 XP_011515638.1 protein mono-ADP-ribosyltransferase PARP10 isoform X2
XM_047422328.1 XP_047278284.1 protein mono-ADP-ribosyltransferase PARP10 isoform X3
XM_047422327.1 XP_047278283.1 protein mono-ADP-ribosyltransferase PARP10 isoform X1
NM_001317895.2 NP_001304824.1 protein mono-ADP-ribosyltransferase PARP10 isoform 2
NM_032789.5 NP_116178.2 protein mono-ADP-ribosyltransferase PARP10 isoform 1

PARP10 Protein Structure

PARP

PARP: Poly(ADP-ribose) polymerase catalytic domain (819 - 1004)

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  • 1025 a.a.
Protein Preferred Names Protein Names

protein mono-ADP-ribosyltransferase PARP10

ADP-ribosyltransferase diphtheria toxin-like 10

poly [ADP-ribose] polymerase 10

Related Agents

Pre-clinical Phase
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-136979 RBN012759 Inhibitor 99.80% Unkown
HY-150207 RBN-3143 Inhibitor 99.24% Unkown
HY-123512 OUL35 Inhibitor 99.84% Unkown
HY-143398 PARP10/15-IN-1 Inhibitor 95.00% Unkown
HY-148566 OUL232 Inhibitor 99.82% Unkown
HY-146502 PARP10/15-IN-3 Inhibitor 99.98% Unkown
HY-146501 PARP10/15-IN-2 Inhibitor 99.00% Unkown
HY-143338 ART-IN-1 Inhibitor 98.91% Unkown
HY-121719 TIQ-A Inhibitor 99.65% Unkown
HY-148754 PARP10-IN-3 Inhibitor 98.89% Unkown
HY-148709 ARTD10/PARP10-IN-1 Inhibitor / Unkown
HY-155993 YCH1899 Inhibitor / Unkown
HY-W294889 OUL245 Inhibitor / Unkown
HY-148710 ARTD10/PARP10-IN-2 Inhibitor / Unkown
HY-148753 PARP10-IN-2 Inhibitor 98.02% Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PARP10 VGNC VGNC:108106
Mus musculus PARP10 MGD MGI:3712326
Rattus norvegicus PARP10 RGD RGD:7744876