Giclanfentrine
Giclanfentrine is a potent PDE3A inhibitor with an IC50 of 0.0058 μM. Giclanfentrine inhibits PDE4B1 activity with an IC50 of 12.9 μM. Giclanfentrine is applicable to studies related to PDE3/cAMP signaling.
For research use only. We do not sell to patients.
- CAS No.: 2408152-69-0
- Formula: C30H35N7O5
- Molecular Weight:573.64
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
PDE3A 0.0058 μM (IC50) |
PDE4B1 12.9 μM (IC50) |
In Vitro
Giclanfentrine (compound 23) inhibits the activities of recombinant PDE3A and PDE4B1 enzymes, with IC50 values of 0.0058 μM and 12.9 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2408152-69-0
-
Molecular Weight 573.64
-
Formula C30H35N7O5
-
SMILES
O=C(C1=C(N=NN1C)O)NCCN2/C(C=C3C4=C(CCN3C2=O)C=C(OCC)C(OC)=C4)=N/C5=C(C)C=C(C)C=C5C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Giclanfentrine Related Classifications
HY-171827 Related Classifications
Powered by Bioz