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Cat. No.: HY-168087

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GSK3335103

GSK3335103 is an orally active, non-peptide α_vβ₆ integrin inhibitor (pIC₅₀=8). GSK3335103 can be used in the study of pulmonary fibrosis.

For research use only. We do not sell to patients.

CAS No.: 1893340-21-0
Formula: C₂₇H₃₆FN₃O₄
Molecular Weight:485.59

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

GSK3335103 Chemical Structure

CAS No.: 1893340-21-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

GSK3335103 is an orally active, non-peptide α_vβ₆ integrin inhibitor (pIC₅₀=8). GSK3335103 can be used in the study of pulmonary fibrosis^[1].

All Integrin Isoforms :

Chemical Information

CAS No. 1893340-21-0
Molecular Weight 485.59
Formula C₂₇H₃₆FN₃O₄
SMILES

O=C(O)C[C@@H](C1=CC=CC(OCCOC)=C1)CN2C[C@@](CCC3=NC4=C(CCCN4)C=C3)(F)CC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Procopiou P A, et al. Discovery and Development of Highly Potent and Orally Bioavailable Nonpeptidic αvβ6 Integrin Inhibitors[J]. Journal of Medicinal Chemistry, 2024. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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GSK3335103

All Integrin Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

GSK3335103 Related Classifications

HY-168087 Related Classifications