BChE-IN-36
hBChE-IN-4 (compound 40) is a potent hCA activator and BChE inhibitor with KA values of 266, 76.9, 918, 893, 98.0 nM for hCA I, hCA II, hCA IV, hCA VB, hCA VII, IC50 values of 72.1, 4.2 nM for eeAChE, eqBChE, respectively. hBChE-IN-4 shows no cytotoxicity. hBChE-IN-4 shows potent procognitive effects. hBChE-IN-4 has the potential for the research of neurodegenerative diseases and other neuropsychiatric disorders.
For research use only. We do not sell to patients.
- Formula: C26H35N5O2
- Molecular Weight:449.59
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
EeAChE 72.1 nM (IC50) |
eqBCHE 4.2 nM (IC50) |
hCA I 266 nM (KA) |
hCA II 76.9 nM (KA) |
hCA VB 893 nM (KA) |
hCA IV 918 nM (KA) |
hCA VII 98.0 nM (KA) |
Chemical Information
-
Molecular Weight 449.59
-
Formula C26H35N5O2
-
SMILES
O=C([C@@H](NCCCCCCNC1=C2CCCCC2=NC3=CC=CC=C31)CC4=CNC=N4)OC
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz