Histone H3 (1-34) 

Histone H3 (1-34) is a peptide derived from human histone isotype 3.1. Histones are the main protein components of eukaryotic chromatin. Histone variants and histone modifications modulate chromatin structure, ensuring the precise operation of cellular processes associated with genomic DNA^[1][2].

3452.00

C₁₄₄H₂₆₀N₅₄O₄₄

Solid

White to off-white

Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Thr-Lys-Ala-Ala-Arg-Lys-Ser-Ala-Pro-Ala-Thr-Gly-Gly

ARTKQTARKSTGGKAPRKQLATKAARKSAPATGG

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light, under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

• [1]. Hake SB, Allis CD. Histone H3 variants and their potential role in indexing mammalian genomes: the "H3 barcode hypothesis". Proc Natl Acad Sci U S A. 2006;103(17):6428-6435.  [Content Brief]

  [2]. Xiong C, et al. Histone Variant H3.3: A versatile H3 variant in health and in disease. Sci China Life Sci. 2016;59(3):245-256.  [Content Brief]

  [3]. Mulder KW, et al. Regulation of histone H3K4 tri-methylation and PAF complex recruitment by the Ccr4-Not complex. Nucleic Acids Res. 2007;35(7):2428-2439.  [Content Brief]