2. PI3K/Akt/mTOR Protein Tyrosine Kinase/RTK Neuronal Signaling
  3. Akt Trk Receptor
  4. HS-345

HS-345 is a TrkA/Ak inhibitor with significant anti-pancreatic cancer effects. HS-345 inhibits the growth and proliferation of pancreatic cancer cells by targeting the TrkA/Akt signaling pathway, while also inducing apoptosis. Additionally, HS-345 suppresses blood vessel formation by decreasing the expression of HIF-1α and VEGF. HS-345 holds promise for research in pancreatic cancer.

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HS-345

HS-345 화학구조

CAS No. : 1462329-41-4

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HS-345 Related Antibodies

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제품 설명

HS-345 is a TrkA/Ak inhibitor with significant anti-pancreatic cancer effects. HS-345 inhibits the growth and proliferation of pancreatic cancer cells by targeting the TrkA/Akt signaling pathway, while also inducing apoptosis. Additionally, HS-345 suppresses blood vessel formation by decreasing the expression of HIF-1α and VEGF. HS-345 holds promise for research in pancreatic cancer[1].

IC50 & Target

TrkA

 

분자량

394.45

화학식

C19H18N6O2S
CAS No.
SMILES

O=S(C1=CC(C2=CN=C(NC=C3C4=CC=NC=C4)C3=C2)=CN=C1N)(N(C)C)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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HS-345 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HS-3451462329-41-4HS345HS 345AktTrk ReceptorPKBProtein kinase BTropomyosin related kinase receptorAnti-cancerInhibitorinhibitorinhibit

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상품명:
HS-345
Cat. No.:
HY-164483
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