Hydrouracil-(4-CP)
Hydrouracil-(4-CP) is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Hydrouracil-(4-CP) can be linked to a target protein ligand via a linker to form a PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 2633726-34-6
- Formula: C10H9ClN2O3
- Molecular Weight:240.64
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2633726-34-6
-
Molecular Weight 240.64
-
Formula C10H9ClN2O3
-
SMILES
O=C1NC(=O)CCN1C2=CC(O)=CC=C2Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)