FCPR16
FCPR16 is a Phosphodiesterase 4 (PDE4) inhibitor. FCPR16 increases the levels of cAMP in SH-SY5Y cells. FCPR16 can be used in the study of Parkinson's disease.
For research use only. We do not sell to patients.
- CAS No.: 1917347-71-7
- Formula: C18H16ClF2NO3
- Molecular Weight:367.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
0.04 μM
Compound: 9; FCPR16
|
Inhibition of human N-terminal GST-tagged PDE4D7 (2 to 748 residues) expressed in baculovirus infected Sf9 cells using cAMP as substrate after 1 hr by fluorescence polarization assay
Inhibition of human N-terminal GST-tagged PDE4D7 (2 to 748 residues) expressed in baculovirus infected Sf9 cells using cAMP as substrate after 1 hr by fluorescence polarization assay
|
[PMID: 30822711] |
| Sf9 | IC50 |
0.17 μM
Compound: 9; FCPR16
|
Inhibition of human full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate incubated for 1 hr by fluorescence polarization assay
Inhibition of human full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate incubated for 1 hr by fluorescence polarization assay
|
[PMID: 30822711] |
Chemical Information
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CAS No. 1917347-71-7
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Molecular Weight 367.77
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Formula C18H16ClF2NO3
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SMILES
O=C(C1=CC=C(C(OCC2CC2)=C1)OC(F)F)NC3=CC=CC=C3Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)