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Cat. No.: HY-18763A

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Indobufen sodium

(Synonyms: Ibustrin sodium)

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

Indobufen sodium is a platelet aggregation inhibitor. Indobufen sodium is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen sodium suppresses thromboxane A₂ (TxA₂) synthesis. Indobufen sodium down-regulates tissue factor (TF) in monocytes.

For research use only. We do not sell to patients.

CAS No.: 94135-04-3
Formula: C₁₈H₁₆NNaO₃
Molecular Weight:317.31

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Indobufen sodium Chemical Structure

CAS No.: 94135-04-3

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Fluorescent Dye

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Biological Activity

Description

All COX Isoforms :

Chemical Information

CAS No. 94135-04-3
Molecular Weight 317.31
Formula C₁₈H₁₆NNaO₃
SMILES

O=C(C(CC)C1=CC=C(N2C(C3=C(C2)C=CC=C3)=O)C=C1)O[Na]
Synonyms

Ibustrin sodium
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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J Pharm Pharmacol

Indobufen alleviates ischemic stroke injury by regulating transcription factor NRF2 and inhibiting ATG5 expression. [Abstract]

2024 Jul 5;76(7):842-850. PMID: 38600790
Neuroreport

Indobufen ameliorates ischemic stroke by suppressing the signal transducer and activator of transcription 1/NIMA-related kinase 7/NOD-like receptor family pyrin domain-containing 3 signaling axis. [Abstract]

2026 Feb 2;37(3):106-117. PMID: 41524599

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Eligini S, et al. Indobufen inhibits tissue factor in human monocytes through a thromboxane-mediated mechanism. Cardiovasc Res. 2006 Jan;69(1):218-26. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Indobufen sodium

2 Cited Publications

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Indobufen sodium

Publications Citing Use of MedChemExpress (MCE) Indobufen sodium

All COX Isoforms

Biological Activity

Chemical Information

Publications (2)

Purity & Documentation

References

Calculators

Help & FAQs

Indobufen sodium Related Classifications

Cat. No.: HY-18763A