1. Terpenoids and Glycosides
  2. Isoescin IB

Isoescin IB 

Cat. No.: HY-N0557
Handling Instructions

Isoescin IB, isolated from horse chestnut tree seeds, is an isomer of Escin IB. Isoescin IB and Escin IB are the chief active ingredients in escin.

For research use only. We do not sell to patients.

Isoescin IB Chemical Structure

Isoescin IB Chemical Structure

CAS No. : 219944-46-4

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Description

Isoescin IB, isolated from horse chestnut tree seeds, is an isomer of Escin IB. Isoescin IB and Escin IB are the chief active ingredients in escin[1].

In Vitro

β-Escin (mainly consisting of escin Ia and escin Ib) is the major active ingredient in horse chestnut seeds extracts. β-escin can inhibit proliferation and/or induce apoptosis in various types of cancer cells including A549 cell, HT-29 cell, HCC cell, OVCAR3 cell and H-Ras 5RP7 cell. β-escin may be useful as a chemopreventive agent, especially for tumors associated with an inflammatory response[1].
As the minor component of escin, α-escin (mainly consisting of isoescin Ia and isoescin Ib) exhibits lower bioactivity[1].

Molecular Weight

1131.26

Formula

C₅₅H₈₆O₂₄

CAS No.

219944-46-4

SMILES
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Isoescin IBOthersEscin IBEscinInhibitorinhibitorinhibit

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